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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
13.33
Human Site:
S772
Identified Species:
22.56
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S772
E
Q
V
L
L
A
Y
S
R
C
L
Q
A
C
G
Chimpanzee
Pan troglodytes
XP_520821
925
103112
K759
K
K
I
F
Q
E
P
K
S
A
H
Q
V
E
Q
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S753
E
Q
V
L
L
A
Y
S
R
C
I
Q
A
C
G
Dog
Lupus familis
XP_543872
907
102087
K741
K
K
I
F
Q
E
P
K
R
A
N
Q
V
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
S725
E
Q
V
L
M
A
Y
S
K
C
I
M
S
C
S
Rat
Rattus norvegicus
XP_001070646
845
94905
S690
E
Q
V
L
T
A
Y
S
T
C
I
A
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
K771
K
K
V
F
Q
E
P
K
K
A
S
Q
V
E
K
Chicken
Gallus gallus
XP_416375
940
105739
K777
K
K
I
F
Q
E
P
K
K
A
N
Q
V
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
K723
K
K
I
F
Q
E
P
K
K
A
S
Q
V
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
S701
E
T
I
S
G
R
K
S
V
F
R
E
V
S
G
Honey Bee
Apis mellifera
XP_001121183
769
88327
E614
Q
V
N
K
I
L
E
E
Y
S
F
Y
I
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
A625
Q
V
L
G
Q
Y
S
A
T
I
E
K
A
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
D703
F
Y
E
A
K
D
G
D
D
I
L
S
G
Y
S
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
H860
Q
K
Y
S
D
V
I
H
S
E
V
R
P
L
S
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
6.6
93.3
13.3
N.A.
60
60
N.A.
13.3
6.6
N.A.
6.6
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
26.6
100
33.3
N.A.
86.6
73.3
N.A.
33.3
33.3
N.A.
33.3
N.A.
33.3
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
29
0
8
0
36
0
8
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
29
0
0
0
36
0
% C
% Asp:
0
0
0
0
8
8
0
8
8
0
0
0
0
0
0
% D
% Glu:
36
0
8
0
0
36
8
8
0
8
8
8
0
36
0
% E
% Phe:
8
0
0
36
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
0
0
0
0
0
8
0
22
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
36
0
8
0
8
0
0
15
22
0
8
0
0
% I
% Lys:
36
43
0
8
8
0
8
36
29
0
0
8
0
8
8
% K
% Leu:
0
0
8
29
15
8
0
0
0
0
15
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
36
0
0
0
0
0
8
0
0
% P
% Gln:
22
29
0
0
43
0
0
0
0
0
0
50
0
0
36
% Q
% Arg:
0
0
0
0
0
8
0
0
22
0
8
8
0
0
0
% R
% Ser:
0
0
0
15
0
0
8
36
15
8
15
8
15
8
36
% S
% Thr:
0
8
0
0
8
0
0
0
15
0
0
0
0
0
0
% T
% Val:
0
15
36
0
0
8
0
0
8
0
8
0
43
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
8
29
0
8
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _